Vega's nephew, Ricardo, was a prominent GDI soldier, and later Forward Battle Commander.
As the commander of Nod forces of the Western hemisphere, Vega was in the position to take control of the Brotherhood, before Kane came to him and brought him into the fold. His rival was Anton Slavik, seen by Vega as his biggest threat. Thus, while pretending to follow Kane, he constantly worked to undermine Slavik and eject him from the Brotherhood.
Vega secretly allied with Kane in the years prior to the Second Tiberium War; at the time, Kane was long thought dead by most of the world and was operating from hiding. Vega's main base of operations was in Honduras, built on an island around an old pre-Columbian pyramid. Its main power came from a hydroelectric dam in southern Mexico.
The outbreak of war
As Kane revealed himself and galvanized GDI, Vega's forces launched a surprise attack on Phoenix Base. Vega was on hand to personally execute Tao, the base's commander.
However, the rest of the Second Tiberium War went badly for Vega. The general was ordered to secure a NodFirst Tiberium War-era "alien warship" from near the Sarajevo Temple and return it to Kane in Cairo. Instead, Vega commandeered it to settle an "old score" in South America and ended up crash landing in the southern United States. This error was compounded by GDI's subsequent capture of the ship, although much of the technology was salvaged by Nod.
Perhaps when McNeil arrives to kill you, you will take sometime to learn from the man. I'm sure he'll teach you lessons you'll carry for the rest of your life, which, by the way, is about seven minutes. - Kane
Tratos, the Forgotten leader, was rescued by GDI from Nod. In return, the Forgotten gave GDI the location of Vega's base. An assault led by GDI Commander Michael McNeil overran the base. Vega's appeals for reinforcements fell on deaf ears; Kane was displeased with the general and opted to destroy the base with a nuclear strike. With no way to escape, Vega overdosed on Eye Candy and died after a brief interrogation at the hands of Commander McNeil.