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Even though it is immobile, it counts as infantry, so that means tanks can drive over them, and anti-infantry vehicles and aircraft are effective against them. Other defensive infantry cannot move over them, which means they're useful to block off a line of defense so that the rest the infantry units won't wonder off leaving their spot unguarded.
The Shredder MG can be upgraded with 'Shrapnel Ammo' to cause more damage against Infantry Units. This costs 750M Credits and 1.5G Research Points.
It is quite strange that they are called Shredder MGs and have the role of anti-infantry, since they are the laser turrets from Tiberium Wars, though this may be because the Shredder Turret has dual shotgun abilities, not machine guns.